Since the 1920s, drying equipments have experienced several years of ups and downs, and they have made considerable progress in the last 20 years, especially since the beginning of the 21st century, with the development of pharmaceuticals, biological products, food, blood products, active substances, etc. With the rapid development of related fields, freeze dryers are increasingly favored by people for their unparalleled technological advantages.

Compared with the freeze-drying technique, drying methods such as drying, boiling, and spray drying need to be performed at a high temperature. For some heat-sensitive materials, problems such as denaturation, deactivation, and oxidation tend to occur. Freeze-drying adopts the principle of sublimation at low temperature, and it can be carried out below zero degree. It can eliminate more than 95% to 99% of the moisture in the material, so that the dried product can be stored for a long time without deterioration.

The application of freeze dryers in medicine includes western medicine and traditional Chinese medicine. Compared with traditional Chinese medicine, the development of western medicine freeze-drying technology is almost mature in China. Especially in the case of injections, the freeze-drying method has resulted in a corresponding increase in the quality and shelf-life of the drugs. Many pharmaceutical plants have therefore been equipped with the relevant freeze-drying equipment. In the field of traditional Chinese medicine, its development is still limited to relatively valuable medicinal species such as ginseng, antler, and Cordyceps sinensis. However, with the development of proprietary Chinese medicines in recent years, the appearance of new Chinese medicine injections and tablets has made it possible for the development of freeze-dried Chinese medicines to have potential for further development.

In the field of biotechnology products, drying technology is widely used in the production of drugs such as serum, plasma, vaccines, enzymes, antibiotics, hormones, etc.; and biochemical inspection drugs, immunology and bacteriological examination drugs; blood, bacteria, arteries, bones , skin, cornea, nerve tissue and various organs are preserved for a long time.

At present, the key to the realization of various refrigeration technologies depends on the development of related professional equipment. Intermittent freeze-drying equipment is currently the mainstream product on the market. The single machine operation is convenient for controlling the different requirements of time, temperature, and vacuum degree when different materials are dried, and is suitable for the production of multiple varieties and small batches. The disadvantage of its products is that it is used for the loading and unloading of materials and the starting time is high, and the production efficiency is not high.

For the limitations of intermittent freeze-drying equipment, a large-scale continuous freeze-drying equipment is being developed internationally. This device can simplify manual operation and management by automating the control system. It is suitable for the drying of a single variety and a large number of materials, especially the production of paste and granular products.

In the development of freeze-drying equipment, foreign countries are obviously superior to domestic products in variety and technology. There are many types of foreign product specifications, and the development of supporting facilities is close. Breakthrough the limitations of single-machine energy saving, starting from the entire dry production chain, the overall energy-saving design. In this regard, relevant industry experts pointed out that in the future development of domestic products, we must improve quality, improve efficiency, shorten time, and reduce energy consumption. Based on the characteristics of the use of different industries in the varieties, further refine the categories, specializing in specialization.

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